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KMID : 0903520010440030137
Journal of the Korean Society of Agricultural Chemistry and Biotechnology
2001 Volume.44 No. 3 p.137 ~ p.142
Physiological Function in vitro of Biopolymer from Bacillus coagulans CE - 74







Abstract
In order to prove physiological function of biopolymer from Bacillus coagulans CE-74, in vitro experiments simulating the passive membrane transport of gastrointestinal tract were carried out using dialysis membrane. And inhibition effect of isolated biopolymer on tyrosinase and angiotensin converting enzyme (ACE) were observed. The glucose retardation index after 30 min dialysis was 43.5% in the presence of 2% biopolymer. As the dialysis period became longer, the retarding effect toward glucose absorption decreased and the effect was close to zero after 5 hr dialysis. The bile acid retardation index after 30 min dialysis was 34% and 44.2% in the presence of 1% and 2% biopolymer, respectively. The effect decreased as the dialysis time elapsed. It was measured by tyrosinase inhibition activity of biopolymer that inhibition effect was 48.5% in 20 §¶/§¡. In a ACE inhibition activity, biopolymer showed inhibition activity as 97% in 10 §¶/§¡.
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